Featured
Researchers Identify Genetic Variants Linked to Age at Natural Menarche and Menopause
A team of US researchers have linked the age of onset of natural menarche and menopause with 10 genetic variants identified at two chromosomal regions and 13 genetic variants at four chromosomal regions, respectively. As the early commencement of menarche and early/late onset of menopause are identified as risk factors for breast and endometrial cancer, osteoporosis, cardiovascular disease, etc., this association marks a crucial step in developing preventive strategies for these conditions. Read more »
Stem Cell Therapy Shows Promise in Treating Stress Urinary Incontinence
Urinary incontinence, a condition characterized by the involuntary loss of urine, is estimated to impair the quality of life of more than 13 million women and around 5 million men, in the US alone. A recent randomized, blinded, multi-dose study reports that autologous muscle-derived cell (AMDC) transplantation into the bladder is safe in wide dosage ranges and effective in relieving the symptoms of stress urinary incontinence (SUI). The study results were presented at the 104th Annual Scientific Meeting of the American Urological Association (AUA), held at Chicago. Read more »
Medicine
Temsirolimus-Bryostatin Combination found Safe and Effective against Metastatic Renal Cell Cancer
Renal cell cancer, the most common type of kidney cancer, develops in the lining of the kidney tubules. Several drugs are being studied to treat the cancer as a... Read more »
De novo Cancers Following Organ Transplantation Have Adverse Outcomes
Several studies suggest that transplant recipients possess a high risk of developing cancer; however, the outcomes of de novo cancer in this population of patients... Read more »
Pharma
Maternal Vitamin D Deficiency Linked to Prevalence of Bacterial Vaginosis during Early Pregnancy
Bacterial vaginosis (BV), the most common vaginal infection affecting women of childbearing age, is linked to adverse pregnancy outcomes, spontaneous preterm birth,... Read more »
Study Demonstrates Prolonged Progression-free Metastatic Breast Cancer Survival with Nab-paclitaxel
A recent multicenter phase II study suggests that weekly administration of nanoparticle albumin-bound (nab)-paclitaxel (ABRAXANE® | Abraxis BioScience, Inc.) has... Read more »
Biotechnology
Urinary Exosomes Serve as Emerging Putative Biomarkers for Aggressive Prostate Cancer
Non-invasive tests, such as prostate specific antigen (PSA) estimation and digital rectal examination, are currently available for the detection of prostate cancer.... Read more »
Study Confirms Autoimmunity of Narcolepsy
The sleep disorder, narcolepsy has been found to arise due to the lack of the hormone hypocretin, which promotes wakefulness. Earlier, researchers have proposed... Read more »
