Human saliva, containing abundant proteins with metabolic, immune response and various cellular functions, such as cell organization, holds great potential in the area of clinical diagnostics. Now, a recent study published in the January issue of the Journal of Proteome Research, has identified about 65 salivary proteins as potential noninvasive biomarkers for the screening, detection, and monitoring of both preclinical and clinical type 2 diabetes. Continue Reading

Osteonecrosis of the jaw (ONJ), secondary to high dose intravenous nitrogen-containing bisphosphonates, is a known adverse effect of this class of drugs; however, the risk with oral administration, believed to be negligible until now has not been studied earlier. Now, a study, published in the latest issue of The Journal of the American Dental Association, has demonstrated that even short-term oral bisphosphonate use may pose a risk for osteonecrosis of the jaw. Continue Reading

A recent study published in the current issue of Journal of Oral and Maxillofacial Surgery has reported that neuro-reflexotherapy (NRT) can be successfully used to treat chronic pain associated with myofascial temporomandibular joint pain (MF/TMJP). Continue Reading

Emdogain® is an enamel matrix derivate (EMD) commonly used for the regeneration of connective tissue, alveolar bone, cementum, and for better attachment of fibers during periodontal surgeries. Now in a controversial new research article published in the latest issue of Oral Oncology, it has been reported that EMD induces the production of gelatinases (MMP-2 and -9), a proteolytic enzyme class, that has been implicated in the development of oral cancer cells and metastasis. Continue Reading

Non-vital or pulpless teeth, being brittle, are more prone to fractures. Now, in a new research article published in the recent issue of the Journal of Dental Research, it has been reported that heat treatment strengths the human dentin, and can be very useful in preventing fractures of the non-vital tooth. Continue Reading

Soft-tissue anesthesia generally lasts longer than pulpal anesthesia, leading to negative consequences such as accidental lip and tongue biting, and difficulty in speaking, smiling, eating and drinking. Now, in a research article published in the latest issue of the Journal of the American Dental Association, it has been reported that phentolamine mesylate (PM) can successfully accelerate the reversal of soft-tissue anesthesia. Continue Reading

Researchers from the University of Michigan School of Dentistry, Michigan, United States, have successfully used stem cells from human exfoliated deciduous teeth (SHED) to produce tissues that closely resemble physiologic dental pulp tissue. The findings of the study are published in the Journal of Endodontics. Continue Reading

Researchers from the University of Bologna, Italy, have reported that calcium silicate dervied from Portland cement (DSC) can be used to desensitize dentin. The findings of this study have been published in the recent issue of the Journal of Dentistry. Continue Reading

The combination of noncoherent visible light and hydrogen peroxide shows promising antibacterial effect against the oral biofilm pathogens according to a new study published in the latest issue of the journal, Antimicrobial Agents and Chemotherapy. Continue Reading

Researchers from the University of Florida, Gainesville, Florida, have reported successful alveolar bone regeneration using extracorporeal shock wave therapy (ESWT). The findings of this study have been published in the recent issue of theJournal of Dental Research. Continue Reading