Emdogain® is an enamel matrix derivate (EMD) commonly used for the regeneration of connective tissue, alveolar bone, cementum, and for better attachment of fibers during periodontal surgeries. Now in a controversial new research article published in the latest issue of Oral Oncology, it has been reported that EMD induces the production of gelatinases (MMP-2 and -9), a proteolytic enzyme class, that has been implicated in the development of oral cancer cells and metastasis. Continue Reading

Non-vital or pulpless teeth, being brittle, are more prone to fractures. Now, in a new research article published in the recent issue of the Journal of Dental Research, it has been reported that heat treatment strengths the human dentin, and can be very useful in preventing fractures of the non-vital tooth. Continue Reading

Soft-tissue anesthesia generally lasts longer than pulpal anesthesia, leading to negative consequences such as accidental lip and tongue biting, and difficulty in speaking, smiling, eating and drinking. Now, in a research article published in the latest issue of the Journal of the American Dental Association, it has been reported that phentolamine mesylate (PM) can successfully accelerate the reversal of soft-tissue anesthesia. Continue Reading

Researchers from the University of Michigan School of Dentistry, Michigan, United States, have successfully used stem cells from human exfoliated deciduous teeth (SHED) to produce tissues that closely resemble physiologic dental pulp tissue. The findings of the study are published in the Journal of Endodontics. Continue Reading

The combination of noncoherent visible light and hydrogen peroxide shows promising antibacterial effect against the oral biofilm pathogens according to a new study published in the latest issue of the journal, Antimicrobial Agents and Chemotherapy. Continue Reading

Researchers from the University of Florida, Gainesville, Florida, have reported successful alveolar bone regeneration using extracorporeal shock wave therapy (ESWT). The findings of this study have been published in the recent issue of theJournal of Dental Research. Continue Reading

Hypodontia, the congenital absence of one or few teeth, may be associated with epithelial ovarian cancer (EOC), according to a new study done by American researchers, Leigh A. Chalothorn, DMD, MS, and her colleagues at the University of Kentucky, Lexington, and University of Virginia, Charlottesville, the findings of which were published in the recent issue of the Journal of American Dental Association.

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In the upcoming issue of the International Endodontic Journal, researchers from the Institute of Oral Biology at the Centre of Dental and Oral Medicine, University of Zurich, Switzerland, have reported that Mineral Trioxide Aggregates (MTA) are superior to calcium hydroxide cements for pulp capping procedures.

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From a clinical standpoint, the treatment of patients with hyperdivergent class II occlusion (long lower anterior facial height and a high mandibular plane angle) is difficult. But in a recent study done at the Regional University Hospital Centre of Lille, Lille, France, researchers successfully treated hyperdivergent class II occlusion cases with complete incision of the pterygomasseteric sling during a sagittal split osteotomy of the mandibular ramus.

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Osteonecrosis of the jaw (ONJ) is one of the major side-effects of prolonged use of bisphosphonates (BPs). But little is known regarding the difference in the risk of ONJ among oral and intravenous (IV) bisphosphonate users. Now, in a recent article published in the Journal of American Dental Association, it has been reported that patients receiving IV BPs are at a higher risk of developing adverse jaw outcomes compared to patients receiving oral BPs.

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